#Hypericum

St. John’s Wort for Depression: Evidence Review

St. John’s Wort (Hypericum perforatum) is one of the most extensively studied herbal antidepressants, with evidence showing it is as effective as SSRIs for mild-to-moderate depression with fewer side effects. However, it has CRITICAL drug interactions that make it unsafe with many medications. This evidence-based guide covers clinical research, mechanism of action, dosing, safety warnings, and the best products.