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#Methylation

2 Articles tagged with "#Methylation"

Biological age testing concept showing DNA methylation patterns on a double helix alongside an epigenetic clock comparing chronological and biological age
Longevity

Biological Age Testing: How Old Are You Really?

Biological age testing uses epigenetic clocks and DNA methylation patterns to measure how fast your body is actually aging—regardless of your birthday. This guide covers the science behind epigenetic clocks like GrimAge, available commercial tests, how to interpret results, and evidence-based interventions that may slow or reverse biological aging.

15 min read
Reviewed
SAMe S-adenosyl methionine molecule diagram showing methylation pathways for neurotransmitter synthesis serotonin dopamine norepinephrine
Mental Wellness

SAMe for Depression: S-Adenosyl Methionine Guide

SAMe (S-adenosyl methionine) is one of the most clinically studied natural compounds for depression, with systematic reviews showing efficacy comparable to prescription antidepressants and fewer side effects. This guide covers the science behind SAMe's methylation-driven antidepressant mechanism, evidence-based dosing protocols (200–1,600 mg/day), critical contraindications including bipolar disorder, and realistic expectations for this effective but expensive supplement.

13 min read
Reviewed